1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-12639AR
    Bephenium (hydroxynaphthoate) (Standard)
    Inhibitor
    Bephenium (hydroxynaphthoate) (Standard) is the analytical standard of Bephenium (hydroxynaphthoate). This product is intended for research and analytical applications.
    Bephenium (hydroxynaphthoate) (Standard)
  • HY-112905
    AN11736
    Inhibitor
    AN11736 is a CPSF3 inhibitor. AN11736 exerts a potent anti-trypsin effect by specifically inhibiting the activity of the trypanosome CPSF3 endonuclease, disrupting the mRNA maturation process. AN11736 exhibits IC50s against T. congolense and T. vivax of 0.14 and 1.3 nM, respectively. AN11736 exhibits strong anti-trypsin activity in mouse and cattle models.
    AN11736
  • HY-N13881
    Amythiamicin C
    Inhibitor
    Amythiamicin C is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum.
    Amythiamicin C
  • HY-107004AR
    Amotosalen hydrochloride (Standard)
    Inhibitor
    Amotosalen hydrochloride (Standard) (S-59 (Standard)) is the analytical standard of Amotosalen (hydrochloride) (HY-107004A). This product is intended for research and analytical applications. Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinKing psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD).
    Amotosalen hydrochloride (Standard)
  • HY-173028
    RH01201
    Inhibitor
    RH01201 is the non-competitive inhibitor for plasmepsin II with a Ki of 123 μM.
    RH01201
  • HY-117241
    AB 3217-B
    Inhibitor
    AB 3217-B is an analog of AB 3217-A and has anti-mite activity.
    AB 3217-B
  • HY-N1581R
    Quassin (Standard)
    Inhibitor
    Quassin (Standard) is the analytical standard of Quassin. This product is intended for research and analytical applications. Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.
    Quassin (Standard)
  • HY-19594R
    Teclozan (Standard)
    Inhibitor
    Teclozan (Standard) is the analytical standard of Teclozan. This product is intended for research and analytical applications. Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections.
    Teclozan (Standard)
  • HY-116004
    Anti-Trypanosoma cruzi agent-5
    Inhibitor
    Anti-Trypanosoma cruzi agent-5 (compoung 8) is a potent inhibitor of Trypanosoma cruzi proliferation.
    Anti-Trypanosoma cruzi agent-5
  • HY-W677714
    SDH-IN-43
    Inhibitor
    SDH-IN-43 (Compound i-19) is a succinate dehydrogenase (SDH) inhibitor. SDH-IN-43 shows potent inhibitory activity against caenorhabditis elegans wirh an IC50 of 6.67 μM. SDH-IN-43 can significantly reduce caenorhabditis elegans reproductive ability and movement ability, and is also effective against drug-resistant strains of Levamisole (HY-A0106), Benzimidazole (HY-Y1825), and Ivermectin (HY-15310). SDH-IN-43 can be used for the research of parasite infection.
    SDH-IN-43
  • HY-14787
    Demiditraz
    Inhibitor
    Demiditraz (PF 3814927) (example 58) is a potent parasiticide. Demiditraz shows potent anti-tick activity against Rhipicephalus sanguineus with an ED100 of 0.1 mg/cm2. Demiditraz can be used for preventing the transmission of tick-borne diseases.
    Demiditraz
  • HY-N5176
    Cephaibol B
    Inhibitor
    Cephaibol B has anti-Gram-positive bacterial activity, but no anti-Gram-negative bacterial activity. Cephaibol B also has the effect of deworming and anti-ectoparasite.
    Cephaibol B
  • HY-159603
    S-WJM992
    Inhibitor
    S-WJM992 (compound 10ahb) is an antiparasitic agent that inhibits ATPase activity under high [Na+] conditions. S-WJM992 also has significant inhibitory effects on parasites that have developed PfATP4 inhibitor-resistance. S-WJM992 is a potential transmission blocker that effectively inhibits gamete development and prevents parasite transmission to mosquitoes via blood feeding.
    S-WJM992
  • HY-149722
    Antiparasitic agent-20
    Inhibitor
    Antiparasitic agent-20 (Compound 1p) is a parasite inhibitor with broad antiparasitic activity. Antiparasitic agent-20 has inhibitory effects on T. brucei and T. cruzi with EC50 values of 0.09 μM and 14.1 μM respectively.
    Antiparasitic agent-20
  • HY-B1885R
    Fenitrothion (Standard)
    Inhibitor
    Fenitrothion (Standard) is the analytical standard of Fenitrothion (HY-B1885). This product is intended for research and analytical applications. Fenitrothion is a broad-spectrum and orally active insecticide/acaricide. Fenitrothion inhibits cholinesterase, AMPKα and IRS1/PI3K/AKT. Fenitrothion causes Apoptosis, reduces SOD activity. Fenitrothion shows insecticidal effect against Rhyzopertha dominica and Tribolium castaneum adults. Fenitrothion is widely used in cotton crops, vegetable crops, fruit crops and field crops, especially rice. Fenitrothion can be used for brain and spleen toxicology studies.
    Fenitrothion (Standard)
  • HY-P5552
    Melimine
    Inhibitor
    Melimine is a hybrid antimicrobial peptide of Melittin (HY-P0233) and Protamine. Melimine is active against P. aeruginosa and S. aureus. Melimine has broad spectrum activity against bacteria, fungi and protozoa.
    Melimine
  • HY-119550
    J1075
    Inhibitor
    J1075 is a selective Schistosoma mansoni HDAC8 inhibitor (with decreased affinity for human HDAC8). J1075 can induce apoptosis (Apoptosis) and death in schistosome cells. J1075 holds research value in the field of anti-parasitic agents.
    J1075
  • HY-120550
    RS 49676
    Inhibitor
    RS 49676 is an N-substituted imidazole compound that exhibits strong in vitro activity against endogenous amoebae (ED50 < 0.1 ng/mL), but is ineffective against exogenous amoebae (epimastigotes). In vivo, RS 49676 (100 mg/kg/d, sc, 2 times) can prolong the average survival time of mice infected with Trypanosoma cruzi to more than 11 weeks.
    RS 49676
  • HY-101590
    Symetine
    Inhibitor
    Symetine is an antiparasitic and antispirochete agent.
    Symetine
  • HY-B0567R
    Dequalinium Chloride (Standard)
    Inhibitor
    Dequalinium (Chloride) (Standard) is the analytical standard of Dequalinium (Chloride). This product is intended for research and analytical applications. Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium chloride is also an antagonist pf α7 nAChR, and an anti-microbial antiseptic agent with a broad bactericidal and fungicidal activity.
    Dequalinium Chloride (Standard)

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